INTRICARE publications

 

Schurgers LJ, Akbulut AC, Kaczor DM, Halder M, Koenen RR, Kramann R
Initiation and Propagation of Vascular Calcification Is Regulated by a Concert of Platelet- and Smooth Muscle Cell-Derived Extracellular Vesicles
Front Cardiovasc Med. 2018 Apr 6;5:36

Bucerius J, Dijkgraaf I, Mottaghy F, Schurgers LJ
Target identification for diagnosis and intervention of vulnerable atherosclerotic plaques beyond 18F-Fluorodeoxyglucose positron emission tompgraphy imaging: promisting tracers on the horizon.
Eur J Nucl Med Mol Imaging. 2018 Oct 9

Koenen RR, Aikawa E
Editorial: Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases
Front Cardiovasc Med. 2018 Sep 19;5:133

Dickhout A, Koenen RR
Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks
Front Cardiovasc Med. 2018 Aug 22;5:113

Fall T, Green D, Qureshi AR, Stenvinkel P, Carlsson AC, Bárány P, Feldreich T, Carrero TJ, Heimbürger O, Ripsweden J, Nowak C, Kalra PA; Vuilleumier N; Ärnlöv J
Circulating proteins as predictors of cardiovascular mortality in end-stage renal disease
J Nephrol. 2019 Feb;32(1):111-119

Reinhold S, Blankesteijn M
Wnt/β-Catenin Inhibitor Dickkopf 1
Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):121-123

Halder M, Petsophonsakul P, Akbulut AC, Pavlic A, Bohan F,  Anderson E, Maresz K, Kramann R, Schurgers L
Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease
Int. J. Mol. Sci. 2019, 20, 896

Mukai H, Dai L, Chen Z, Lindholm B, Ripsweden J, Brismar T, Heimbürger O, Barany P, Qureshi A, Söderberg M, Bäck M, Stenvinkel P
Inverse J-shaped relation between coronary arterial calcium density and mortality in advanced chronic kidney disease
Neprhol Dial Transplant, 2018, 1-9

Karlöf E, Seime T, Dias N, Lengquist M, Witasp A, Almqvist H, Kronqvist M, Gadin J, Odeberg J, Maegdefessel L, Stenvinkel P, Perisic Matic L, Hedin U
Correlation of computed tomography with carotic plaque transcriptomes associates calcificationto lesion-stabilization
Atherosclerosis. 2019 Sep;288:175-185

Phan F, Aubert CE, Perisic Matic L, Funck-Brentano C, Hartemann A, Stenvinkel P, Halbron M, Kemel S, Witasp A, Carlier A, Amouyal C, Massy ZA, Bourron O, Lacorte J-M,  Salem J-E, Lajat-Kiss F, Liabeuf S
Serum concentration and vascular expression of adiponectin are differentially associated with the diabetic calcifying peripheral arteriopathy
Diabetol Metab Syndr. 2019 Apr 29;11:32

Truijman MTB, Mess WH, Heeneman S, van Oostenbrugge RJ, Nelemans PJ, Schreuder FHBM, Daemen J-W HC, van Hoof RHM, Nederkoorn PJ, Vöö S, Daemen MJAP, Crombag GAJC, Kooi ME, Wildberger JE, Wijnen NJA
Microvasculature and intraplaque hemorrhage in atherosclerotic carotid lesions: a cardiovascular magnetic resonance imaging study
J Cardiovasc Magn Reson. 2019 Mar 4;21(1):15

Jaminon A, Reesink K, Kroon A, Schurgers L
The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes
Int J Mol Sci. 2019 Nov 14;20(22):5694

Wasilewski GB, Vervloet MG, Schurgers LJ
The Bone-Vasculature Axis: Calcium Supplementation and the Role of Vitamin K
Front Cardiovasc Med. 2019 Feb 5;6:6

Artiach G, Carracedo M, Seime T, Plunde O, Laguna-Fernandez A, Matic L, Franco-Cereceda A, Bäck M
Proteoglycan 4 is Increased in Human Calcified Aortic Valves and Enhances Valvular Interstitial Cell Calcification
Cells. 2020 Mar 11;9(3):684

Röhl S, Rykaczewska U, Seime T, Suur BE, Gonzalez Diez M, Gådin JR, Gainullina A, Sergushichev AA, Wirka R, Lengquist M, Kronqvist M, Bergman O, Odeberg J, Lindeman JHN, Quertermous T, Hamsten A, Eriksson P, Hedin U, Razuvaev A, Perisic Matic L
Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response.
In press at J Vasc Surg-Vasc Sci

Dai L, Qureshi AR, Witasp A, Lindholm B, Stenvinkel P
Early Vascular Ageing and Cellular Senescence in Chronic Kidney Disease
Computational and Structural Biotechnology Journal, 2020, 17, 721-729

Dai L, Schurgers LJ, Shiels PG, Stenvinkel P
Early vascular ageing in chronic kidney disease: impact of inflammation, vitamin K, senescence and genomic damage
Nephrol Dial Transplant. 2020, 35(Suppl 2):ii31-ii27

Dai L, Plunde O, Qureshi R, Lindholm B, Brismar TB, Schurgers LJ, Söderberg M, Ripsweden J, Bäck M, Stenvinkel P
Aortic Valve Calcium Associates with All-Cause Mortality Independent of Coronary Artery Calcium and Inflammation in Patients with End-Stage Renal Disease
Journal of Clinical Medicine 9/0: 607

Heuschkel MA, Skenteris N-T,  Hutcheson JD, Van der Valk DD, Bremer J, Goody P, Hjortnaes J, Jansen F, Bouten C, Van den Bogaerdt A, Matic L, Marx N, Goettsch C
Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits
Cells. 2020 Sep 24;9(10):2164

Golembiewska E, Qureshi AR, Dai L, Lindholm B, Heimbürger O, Söderberg M, Brismar TB, Ripsweden J, Barany P, Johnson RJ, Stenvinkel P
Copeptin is independently associated with vascular calcification in chronic kidney disease stage 5
BMC Nephrology, 2020, 21, 43

Jankowski J, Böhm M, Orth-Alampour S, Holmar J, Noels H, Bhargava S
Development, establishment and validation of in vitro and ex vivo assays of vascular calcification
Biochem Biophys Res Commun.,2020, 17;530(2):462-470

Altunay B, Morgenroth A, Beheshti M, Vogg A, Wong NCL, Ting H, Biersack H-J, Stickeler E, Mottaghy FM
HER2-directed antibodies, affibodies and nanobodies as drug-delivery vehicles in breast cancer with a specific focus on radioimmunotherapy and radioimmunoimaging
Eur J Nucl Med Mol Imaging. 2020

Crombag G, Hoof RHM van, Holtackers RJ, Schreuder FHBM, Truijman MT, Schreuder T, Orshoven NP Van, Mess WH, Hofman PAM, Oostenbrugge RJ van, Wildberger JE, Kooi ME
Symptomatic Carotid Plaques Demonstrate Less Leaky Plaque Microvasculature Compared With the Contralateral Side: A Dynamic Contrast‐Enhanced Magnetic Resonance Imaging Study
J Am Heart Assoc. 2019 Apr 16;8(8):e011832

Furmanik M, Chatrou ML, Gorp R van, Akbulut AC, Willems BAG, Schmidt HHHW, Eys GJJM van, Bochaton-Piallat M-L, Proudfoot D, Biessen EAL, Hedin U, Perisic L, Mees B, Shanahan C, Reutelingsperger CPM, Schurgers LJ,
Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification
Circ Res. 2020 Sep 11;127(7):911-927

Dai L, Meijers BK, Bammens B, Loor H de, Schurgers LJ, Qureshi AR, Stenvinkel P, Evenepoel P
Sevelamer Use in End-Stage Kidney Disease (ESKD) Patients Associates with Poor Vitamin K Status and High Levels of Gut-Derived Uremic Toxins: A Drug-Bug Interaction?
Toxins (Basel). 2020 May 27;12(6):351

Samal SK, Qureshi AR, Rahman M, Stenvinkel P, Frostegård J
Different subclasses and isotypes of antibodies against phosphorylcholine in haemodialysis patients: association with mortality
Clin Exp Immunol. 2020 Jul;201(1):94-104

Samal SK, Qureshi AR, Rahman M, Stenvinkel P, Frostegård J
Antibodies against Malondialdehyde in Haemodialysis Patients and Its Association with Clinical Outcomes: Differences between Subclasses and Isotypes
J Clin Med. 2020 Mar 11;9(3):753

Aizaz M, Moonen RPM, van der Pol JAJ, Prieto C, Botnar RM, ME
PET/MRI of atherosclerosis
Cardiovasc Diagn Ther. 2020 Aug;10(4):1120-1139

Akbulut AC, Pavlic A, Petsophonsakul P, Halder M, Maresz K, Kramann R, Schurgers L
Vitamin K2 Needs an RDI Separate from Vitamin K1
Nutrients. 2020 Jun 21;12(6):1852

Florea A, Morgenroth A, Bucerius J, Schurgers LJ, Mottaghy, FM
Locking and Loading the Bullet Against Micro-Calcification
Eur J Prev Cardiol 2020 Mar 2:2047487320911138

Jaminon AMG, Dai L, Qureshi AR, Evenepoel P, Ripsweden J, SöderbergM, Witasp A, Olauson H, Schurgers LJ & Stenvinkel P
Matrix Gla protein is an independent predictor of both intimal and medial vascular calcification in chronic kidney disease
Sci Rep. 2020 Apr 20;10(1):6586

Dai L, Debowska M, Lukaszuk T, Bobrowski L, Barany P, Söderberg M, Thiagarajan D, Frostegård J, Wennberg L, Lindholm B, Qureshi AR, Waniewski J, Stenvinkel P
Phenotypic features of vascular calcification in chronic kidney disease
J Intern Med. 2020 Apr;287(4):422-434

Akbulut AC, Wasilewski GB, Rapp N, Forin F, Singer H, Czogalla-Nitsche KJ, and Schurgers LJ
Menaquinone-7 Supplementation Improves Osteogenesis in Pluripotent Stem Cell Derived Mesenchymal Stem Cells
Front. Cell Dev. Biol., 28 January 2021

Reinhold S, Blankesteijn M, Foulquier S
The Interplay of WNT and PPARy signaling in vascular calcification
Cells 2020, 9(12), 2658

Crombag GAJC, Spronk HM, Nelemans P, Schreuder FHBM, Truijman MTB, van Dijk AC, de Rotte AAJ, Liem MI, Daemen MJAP, van der Steen AFW, Mess WH, Nederkoorn PJ, Hendrikse J, van der Lugt A, Wildberger JE, Ten Cate H, van Oostenbrugge RJ, Kooi ME
No Association between Thrombin Generation and Intra-Plaque Haemorrhage in Symptomatic Carotid Atherosclerotic Plaques: The Plaque at RISK (PARISK) Study
Thromb Haemost 2018;118:1461–1469

Kassem M, Florea A, Mottaghy FM, van Oostenbrugge R, Kooi ME
Magnetic resonance imaging of carotid plaques: current status and clinical perspectives
Ann Transl Med 2020;8(19):1266

van Dijk AC, Donkel SJ, Zadi T, Sonneveld MAH, Schreuder FHBM, Chohan MF, Koudstaal PJ, Leebeek FWG, Saxena R, Hendrikse J, Kooi ME, van der Lugt A, de Maat MPM
Association between fibrinogen and fibrinogen γ’ and atherosclerotic plaque morphology and composition in symptomatic carotid artery stenosis: Plaque-At-RISK study
Thrombosis Research  VOLUME 177, P130-135, MAY 01, 2019

Röhl S, Rykaczewska U, Seime T, Suur BE, Gonzalez Diez M, Gådin JR, Gainullina A, Sergushichev AA, Wirka, Lengquist M, Kronqvist M, Bergman O, Odeberg, Lindeman JHN, Quertermous T, Hamsten A, Eriksson P, Hedin U, Razuvaev A, Perisic Matic L
Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response
JVS: Vascular Science. 2020; 1:13-27

Seime T, Akbulut AC, Liljeqvist ML, Siika A, Jin H, Winski G, van Gorp RH, Karlöf E, Lengquist M, Buckler AJ, Kronqvist M, Waring OJ, Lindeman JHN, Biessen EAL, Maegdefessel L, Razuvaev A, Schurgers LJ, Hedin U, Matic L
Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification
Cells. 2021; 10(6):1276

Dai L, Schurgers L, Shiels PG, Stenvinkel P
A biomimetic natural sciences approach to understanding the mechanisms of ageing in burden of lifestyle diseases
Clin Sci (Lond). 2021 May 28;135(10):1251-1272

Kuppe C, Ibrahim MM, Kranz J, Zhang X, Ziegler S, Perales-Patón J, Jansen J, Reimer KC, Smith JR, Dobie R, Wilson-Kanamori JR, Halder M, Xu Y, Kabgani N, Kaesler N, Klaus M, Gernhold L, Puelles VG, Huber TB, Boor P, Menzel S, Hoogenboezem RM, Bindels EMJ, Steffens J, Floege J, Schneider RK, Saez-Rodriguez J, Henderson NC, Kramann R
Decoding myofibroblast origins in human kidney fibrosis
Nature. 2021 Jan;589(7841):281-286

Samal SK, Fröbert O, Kindberg J, Stenvinkel P, Frostegård J
Potential natural immunization against atherosclerosis in hibernating bears
Sci Rep. 2021 Jun 9;11(1):12120